Description

Miconazole Nitrate CAS NO 228321-87-7 is a synthetic imidazole antifungal agent, widely recognized for its potent activity against a broad spectrum of pathogenic fungi and yeasts. Its primary value lies in its effectiveness as a key active pharmaceutical ingredient (API) for topical and systemic antifungal formulations. This compound is essential for manufacturers in the pharmaceutical, veterinary, and personal care industries requiring a reliable, high-purity antifungal component.

Application

• Pharmaceutical API: Core ingredient in topical creams, ointments, powders, and sprays for treating athlete's foot, ringworm, jock itch, and cutaneous candidiasis.
• Veterinary Medicine: Used in antifungal preparations for treating dermatological infections in companion animals and livestock.
• Personal Care Products: Incorporated into medicated soaps, shampoos, and foot care products for antifungal and anti-dandruff properties.
• Oral & Vaginal Formulations: Serves as the active agent in lozenges for oral thrush and in pessaries/creams for vulvovaginal candidiasis.
• Industrial Preservative: Potential application as a fungistatic agent in certain industrial products and material coatings susceptible to fungal growth.

Basic Information

Product Name	Miconazole Nitrate
CAS No.	228321-87-7
Molecular Formula	C18H14Cl4N2O • HNO3
Molecular Weight	479.15 g/mol
Synonyms	Miconazole Nitrate; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate; Micatin; Monistat; Daktarin; Gyno-Daktarin; Albistat; Miconazole (as nitrate salt)
EINECS	Contact for details

Quality Control

Our Miconazole Nitrate is manufactured under strict quality management systems. It is tested to meet stringent specifications, including identification, assay, impurity profile, and residual solvents, aligning with major pharmacopoeial standards such as USP, EP, and BP. A comprehensive Certificate of Analysis (COA) is provided with each batch to ensure traceability and compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.