Description

(4-Fluoro-3-Iodophenyl)Methanol is a versatile halogenated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and iodine substituents, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis, such as cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized monomers for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes due to its modifiable benzyl alcohol group.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	(4-Fluoro-3-Iodophenyl)Methanol
CAS No.	227609-87-2
Molecular Formula	C7H6FIO
Molecular Weight	252.03 g/mol
Synonyms	4-Fluoro-3-iodobenzyl alcohol; (4-Fluoro-3-iodophenyl)methanol; 3-Iodo-4-fluorobenzyl alcohol; 1-(Hydroxymethyl)-4-fluoro-3-iodobenzene; α-Hydroxy-4-fluoro-3-iodotoluene; 4-Fluoro-3-iodo-benzenemethanol; Benzenemethanol, 4-fluoro-3-iodo-
EINECS	Contact for details

Quality Control

Our (4-Fluoro-3-Iodophenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.