Description

3-Thiophenecarbonyl Chloride, 4-Methoxy- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a reactive acyl chloride derivative, enabling the efficient introduction of the 4-methoxythiophene-3-carbonyl moiety into target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed to create novel thiophene-based ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probe Synthesis: Useful for labeling and modifying biomolecules to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Thiophenecarbonyl Chloride, 4-Methoxy- (9Ci)
CAS No.	224649-28-9
Molecular Formula	C6H5ClO2S
Molecular Weight	176.62 g/mol
Synonyms	4-Methoxythiophene-3-carbonyl chloride; 4-Methoxy-3-thiophenecarboxylic acid chloride; 3-Carbonyl chloride-4-methoxythiophene; 4-Methoxy-thiophene-3-carbonyl chloride; 4-Methoxy-3-thienoyl chloride; 3-Thienoyl chloride, 4-methoxy-; 4-Methoxy-3-thiophenecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarbonyl Chloride, 4-Methoxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO 9001 compliant workflows for our global partners in research and development.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.