Description

4-Isothiocyanato-n-Methylbenzenesulfonamide is a specialized organic sulfonamide derivative featuring a reactive isothiocyanate functional group. This compound is valued as a key synthetic intermediate for constructing more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for the development of novel active ingredients and chemical probes.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, especially those targeting enzyme inhibition.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or pesticides where the sulfonamide and isothiocyanate moieties confer specific biological activity.
• Chemical Biology Probe: Acts as a reactive handle for labeling or modifying proteins, peptides, and other biomolecules in biochemical studies.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialized polymers with unique thermal or chemical resistance properties.
• Organic Synthesis: A versatile reagent for introducing the N-methylsulfonamide and isothiocyanate groups into more complex molecular architectures.

Basic Information

Product Name	4-Isothiocyanato-n-Methylbenzenesulfonamide
CAS No.	223785-90-8
Molecular Formula	C8H8N2O2S2
Molecular Weight	228.29 g/mol
Synonyms	N-Methyl-4-isothiocyanatobenzenesulfonamide; p-Isothiocyanato-N-methylbenzenesulfonamide; 4-Isothiocyanato-N-methylbenzenesulfonamide; Benzenesulfonamide, N-methyl-4-isothiocyanato-; Tosyl isothiocyanate, N-methyl derivative
EINECS	Contact for details

Quality Control

Our 4-Isothiocyanato-n-Methylbenzenesulfonamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.