Description

[5-(4-Fluorophenyl)Pyridin-3-Yl]Methanol is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex pharmacophores and functional materials. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorophenyl-pyridine moiety contributes to biological activity and stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	[5-(4-Fluorophenyl)Pyridin-3-Yl]Methanol
CAS No.	222551-22-6
Molecular Formula	C12H10FNO
Molecular Weight	203.21 g/mol
Synonyms	(5-(4-Fluorophenyl)pyridin-3-yl)methanol; 3-Pyridinemethanol, 5-(4-fluorophenyl)-; 5-(4-Fluorophenyl)-3-pyridinemethanol; 5-(p-Fluorophenyl)nicotinyl alcohol; (5-(4-Fluorophenyl)-3-pyridyl)methanol; 222551-22-6; 5-(4-Fluorophenyl)pyridine-3-methanol
EINECS	Contact for details

Quality Control

Our [5-(4-Fluorophenyl)Pyridin-3-Yl]Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.