Description

1H-Pyrrole-3-Carbonyl Chloride, 1-Phenyl- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key acylating agent, enabling the efficient introduction of the 1-phenylpyrrole-3-carbonyl moiety into complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials. Its reactive carbonyl chloride group makes it a versatile intermediate for constructing amide and ester linkages under controlled conditions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the pyrrole scaffold can impart specific biological activity.
• Material Science Research: Serves as a building block for creating functional organic materials, such as conductive polymers or organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical and custom synthesis houses producing high-value, low-volume specialty chemicals for clients.

Basic Information

Item	Details
Product Name	1H-Pyrrole-3-Carbonyl Chloride, 1-Phenyl- (9Ci)
CAS No.	220968-56-9
Molecular Formula	C11H8ClNO
Molecular Weight	205.64 g/mol
Synonyms	1-Phenyl-1H-pyrrole-3-carbonyl chloride; 1-Phenylpyrrole-3-carbonyl chloride; 1-Phenyl-1H-pyrrole-3-carboxylic acid chloride; 3-(Chlorocarbonyl)-1-phenyl-1H-pyrrole; 1-Phenylpyrrole-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-3-Carbonyl Chloride, 1-Phenyl- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.