Description

Omeprazole Sulfide Hydrochloride is a key pharmaceutical intermediate and impurity standard used in the synthesis and quality control of proton pump inhibitors. This compound is critical for ensuring the purity, safety, and efficacy of final drug products by serving as a reference marker for related substances. It is primarily required by pharmaceutical manufacturers, analytical laboratories, and research institutions engaged in drug development and regulatory compliance.

Application

• Primary reference standard for the identification and quantification of related impurities in Omeprazole and its pharmaceutical formulations.
• Critical intermediate in the research, development, and synthesis of proton pump inhibitor (PPI) drugs.
• Essential component in analytical method development and validation for pharmaceutical quality control (QC) and quality assurance (QA).
• Used in stability studies to monitor degradation pathways and ensure drug product shelf-life.
• Valuable chemical reagent in academic and industrial research focused on gastroesophageal therapeutics.
• Serves as a building block for the preparation of other specialized sulfur-containing pharmaceutical compounds.

Basic Information

Product Name	Omeprazole Sulfide Hydrochloride
CAS No.	220757-75-5
Molecular Formula	C17H20N3O2S•HCl
Molecular Weight	367.88 g/mol (Hydrochloride salt)
Synonyms	5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole Hydrochloride; Omeprazole Impurity F (Hydrochloride); Omeprazole Sulfide HCl; Omeprazole Related Compound F HCl; 5-Methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-1,3-benzodiazole Hydrochloride
EINECS	Contact for details

Quality Control

Our Omeprazole Sulfide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade standards suitable for pharmaceutical analysis and synthesis. A detailed Certificate of Analysis (COA) with batch-specific data is provided to guarantee traceability and consistency for your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.