Description

1-(3,5-Dimethylphenyl)-2,2,2-Trifluoroethan-1-Ol is a high-purity fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, combining a trifluoroethanol moiety with a dimethylphenyl group, which are valuable for modulating the physicochemical properties of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of biologically active molecules, particularly those requiring trifluoromethyl or trifluoroethanol groups to enhance metabolic stability, lipophilicity, or binding affinity.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atoms can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modification: Incorporated into specialty polymers to impart specific characteristics such as chemical resistance, thermal stability, or altered surface properties.
• Catalyst & Ligand Development: Utilized in the synthesis of novel chiral ligands or organocatalysts for asymmetric synthesis applications.
• Chemical Research & Development: A versatile reagent for exploratory chemistry in academic and industrial laboratories focused on fluorine chemistry and medicinal chemistry.

Basic Information

Product Name	1-(3,5-Dimethylphenyl)-2,2,2-Trifluoroethan-1-Ol
CAS No.	220675-94-5
Molecular Formula	C10H11F3O
Molecular Weight	204.19 g/mol
Synonyms	α-(Trifluoromethyl)-3,5-dimethylbenzenemethanol; 2,2,2-Trifluoro-1-(3,5-dimethylphenyl)ethanol; 1-(3,5-Dimethylphenyl)-2,2,2-trifluoroethanol; 3,5-Dimethyl-α-(trifluoromethyl)benzyl Alcohol; (3,5-Dimethylphenyl)(trifluoromethyl)methanol; Benzenemethanol, α-(trifluoromethyl)-3,5-dimethyl-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer various grades, including standard and high-purity, tailored to specific application needs. Each batch is characterized and controlled using advanced analytical techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0% (Standard Grade) ≥99.0% (High Purity Grade)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.