Description

Repifermin is a recombinant human keratinocyte growth factor-2 (KGF-2) protein, a critical signaling molecule involved in epithelial cell proliferation and differentiation. Its primary value lies in advanced pharmaceutical research and development, particularly for therapeutic applications targeting tissue repair and mucosal healing. This product is essential for researchers and developers in the biopharmaceutical industry focusing on wound healing, gastrointestinal disorders, and regenerative medicine. We supply high-purity Repifermin to support your critical R&D and preclinical studies.

Application

• Pharmaceutical R&D: Core material for developing novel biologics aimed at epithelial tissue repair and regeneration.
• Wound Healing Research: Investigation of mechanisms and potential therapies for acute and chronic wounds, including diabetic ulcers.
• Mucositis Treatment Studies: Preclinical research for preventing or treating oral and gastrointestinal mucositis, a common side effect of chemotherapy and radiotherapy.
• Regenerative Medicine: Exploration in tissue engineering applications for skin, bladder, and gastrointestinal tract reconstruction.
• Cell Culture & Biochemistry: Used as a growth factor supplement in specialized cell culture systems to study epithelial cell biology.
• Biomarker & Mechanism Studies: Tool for understanding the KGF signaling pathway and its role in various disease states.

Basic Information

Product Name	Repifermin
CAS No.	219527-63-6
Molecular Formula	C816H1321N233O255S9
Molecular Weight	Approx. 19.4 kDa
Synonyms	Keratinocyte Growth Factor-2 (KGF-2); Palifermin (processed form); Recombinant Human KGF-2; FGF-10; Fibroblast Growth Factor-10; Fibroblast Growth Factor 10; HBGF-10; Heparin-binding growth factor 10; KGF2
EINECS	Contact for details

Quality Control

Our Repifermin is manufactured under strict quality systems suitable for research applications. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, potency, and consistency. Certificates of Analysis (COA) are provided, detailing results for key parameters such as purity by HPLC, bioactivity, endotoxin levels, and sterility where applicable. We are committed to supplying material that meets the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture uptake. For aliquots, use sterile, low-protein-binding tubes. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/MS)	Conforms to standard
Purity (SDS-PAGE & RP-HPLC)	≥ 95%
Potency (Cell-based assay)	Contact for details
Endotoxin	< 1.0 EU/µg
Protein Content (UV/A280)	Contact for details
Solubility	Soluble in sterile PBS or cell culture medium

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.