Description

3-(2-Chlorophenyl)-6-Fluoro-2-[[(2-Fluorophenyl)Amino]Methyl]-4(3H)-Quinazolinone is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly for creating targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinazolinone-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Oncology Drug Development: Serves as a core scaffold for potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Investigated for the development of new agents targeting neurological disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for chemical biology and pharmacological studies.

Basic Information

Product Name	3-(2-Chlorophenyl)-6-Fluoro-2-[[(2-Fluorophenyl)Amino]Methyl]-4(3H)-Quinazolinone
CAS No.	217942-71-7
Molecular Formula	C21H14ClF2N3O
Molecular Weight	397.81 g/mol
Synonyms	2-[(2-Fluorophenyl)aminomethyl]-3-(2-chlorophenyl)-6-fluoro-4(3H)-quinazolinone; 3-(2-Chlorophenyl)-6-fluoro-2-[[(2-fluorophenyl)amino]methyl]-4(3H)-quinazolinone; 6-Fluoro-3-(2-chlorophenyl)-2-[(2-fluorophenylamino)methyl]-3H-quinazolin-4-one; 217942-71-7; Quinazolinone derivative, 6-fluoro-3-(2-chlorophenyl)-2-[(2-fluorophenylamino)methyl]-; 2-[(2-Fluorophenylamino)methyl]-3-(2-chlorophenyl)-6-fluoro-4(3H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 3-(2-Chlorophenyl)-6-Fluoro-2-[[(2-Fluorophenyl)Amino]Methyl]-4(3H)-Quinazolinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of this high-value intermediate for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.