Description

Ethaselen is a potent and selective thioredoxin reductase (TrxR) inhibitor, representing a significant class of organoselenium compounds with targeted biological activity. This compound matters for researchers and developers seeking to modulate redox signaling pathways, which are implicated in various disease states. It is primarily needed by the pharmaceutical and biotechnology sectors for use in preclinical research, drug discovery programs, and as a reference standard in analytical chemistry.

Application

• Pharmaceutical Research & Development: As a key investigational agent for studying the role of thioredoxin reductase in cancer, inflammation, and neurodegenerative diseases.
• Biochemical Research: Used as a specific tool compound to inhibit TrxR activity in cell-based and enzymatic assays to elucidate redox biology mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and other analytical techniques.
• Drug Discovery: A lead compound for the development of novel chemotherapeutic and chemopreventive agents targeting antioxidant systems in cells.
• Academic Research: Utilized in university and institutional labs for fundamental studies in biochemistry, pharmacology, and molecular biology.

Basic Information

Product Name	Ethaselen
CAS No.	217798-39-5
Molecular Formula	C11H9NO2Se
Molecular Weight	274.16 g/mol
Synonyms	1,2-Benzisoselenazol-3(2H)-one, 2-(1-Oxoethyl)-; BBSKE; Ethaselenum; 2-Acetyl-1,2-benzisoselenazol-3(2H)-one; 2-Acetyl-3H-1,2-benzisoselenazol-3-one; TrxR Inhibitor Ethaselen; Selective Thioredoxin Reductase Inhibitor
EINECS	Contact for details

Quality Control

Our Ethaselen is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.