Description

3-Bromo-5-Fluorobenzyl Alcohol is a versatile halogenated benzyl alcohol derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine substituents on the aromatic ring, which allows for selective functionalization and the introduction of unique physicochemical properties into target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Heck) to construct complex biaryl structures.
• Fine Chemical & Specialty Polymer Production: Intermediate for creating specialized monomers, ligands for catalysis, and performance chemicals.

Basic Information

Product Name	3-Bromo-5-Fluorobenzyl Alcohol
CAS No.	216755-56-5
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	(3-Bromo-5-fluorophenyl)methanol; 3-Bromo-5-fluorobenzenemethanol; 5-Fluoro-3-bromobenzyl Alcohol; 1-Bromo-3-fluoro-5-(hydroxymethyl)benzene; α-Hydroxymethyl-3-bromo-5-fluorobenzene; 3-Bromo-5-fluoro-benzenemethanol; 3-Bromo-5-fluoro-benzylalcohol
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluorobenzyl Alcohol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, for comprehensive identity and purity verification. A Certificate of Analysis (COA) detailing all relevant specifications is provided with each shipment. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.