Description

Benzo[B]Thiophene-2-Carbonyl Chloride, 5-Amino- (9Ci) is a high-value, multifunctional chemical building block characterized by its reactive carbonyl chloride and amino substituents on a benzothiophene scaffold. This compound is essential for the synthesis of complex heterocyclic molecules, enabling the development of novel materials and active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for its role in creating new compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology, neurology, and anti-infective research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science Research: Serves as a precursor for organic semiconductors, liquid crystals, and other functional materials due to the benzothiophene core.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments where the amino and carbonyl chloride groups allow for color tuning and polymer attachment.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes and diagnostics.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	Benzo[B]Thiophene-2-Carbonyl Chloride, 5-Amino- (9Ci)
CAS No.	215941-03-0
Molecular Formula	C10H6ClNOS
Molecular Weight	223.68 g/mol
Synonyms	5-Aminobenzo[b]thiophene-2-carbonyl chloride; 5-Amino-2-benzothiophenecarbonyl chloride; 2-Benzothiophenecarbonyl chloride, 5-amino-; 5-Amino-benzo[b]thiophene-2-carbonyl chloride; 5-Amino-1-benzothiophene-2-carbonyl chloride; 5-Aminothianaphthene-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-2-Carbonyl Chloride, 5-Amino- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.