Description

1H-Indole-6-Carbonyl Chloride (9Ci) is a versatile and highly reactive organic building block, essential for constructing complex molecular architectures. Its core value lies in its acyl chloride functionality, which enables efficient amide bond formation and other key transformations in synthetic chemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalization agent for creating specialized polymers and organic electronic materials.
• Peptide Mimetics: Employed to incorporate the indole scaffold into peptide chains, modifying their biological activity and stability.
• Chemical Biology Probes: Utilized to label proteins or other biomolecules for study in biochemical assays and diagnostic research.
• Academic & Contract Research: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	1H-Indole-6-Carbonyl Chloride (9Ci)
CAS No.	215941-02-9
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	6-Carboxyindole Hydrochloride; Indole-6-carbonyl chloride; 1H-Indole-6-carbonyl chloride; 6-Indolecarbonyl chloride; 6-(Chlorocarbonyl)-1H-indole; 215941-02-9; 6-Carboxy-1H-indole acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Indole-6-Carbonyl Chloride is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the rigorous demands of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.