Description

2-Chloro-N6-Cyclopentyl 2'-Deoxy- Adenosine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and a key intermediate in the synthesis of novel therapeutic agents, particularly those targeting specific enzymatic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral and anticancer drugs, as well as in biochemical studies exploring nucleotide metabolism and receptor interactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel adenosine receptor agonists and antagonists for therapeutic development.
• Antiviral Drug Research: Used in the design and synthesis of nucleoside analogs with potential activity against viral polymerases.
• Oncology Research: Investigated as a building block for prodrugs and targeted cancer therapies that interfere with DNA synthesis.
• Biochemical Tool Compound: Employed in enzymatic studies to investigate the substrate specificity and inhibition of kinases and other nucleotide-binding proteins.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2-Chloro-N6-Cyclopentyl 2'-Deoxy- Adenosine
CAS No.	215108-39-7
Molecular Formula	C15H20ClN5O3
Molecular Weight	353.80 g/mol
Synonyms	2-Chloro-N6-cyclopentyl-2'-deoxyadenosine; 2-Chloro-2'-deoxy-N6-cyclopentyladenosine; 2-Cl-N6-CPA; 2'-Deoxy-2-chloro-N6-cyclopentyladenosine; 2-Chloro-N6-cyclopentyladenosine 2'-deoxy; Adenosine, 2-chloro-2'-deoxy-N6-cyclopentyl-; 2-Chloro-N6-cyclopentyl-2'-deoxy-adenosine; 2-Cl-cd-Ado
EINECS	Contact for details

Quality Control

Our 2-Chloro-N6-Cyclopentyl 2'-Deoxy- Adenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.