Description

2H-1-Benzopyran-5-Carbonyl Chloride, 8-Fluoro- (9Ci) is a high-purity, reactive chemical intermediate belonging to the benzopyran family. This compound is critical for the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated benzopyran derivatives with potential biological activity.
• Agrochemical Research: Used in creating novel active ingredients for crop protection products.
• Material Science: Serves as a precursor for advanced organic materials and functional polymers.
• Chemical Synthesis: Reactive acyl chloride group enables amide and ester bond formation in complex multi-step syntheses.
• Fluorine Chemistry: The 8-fluoro substituent makes it valuable for studying structure-activity relationships in medicinal chemistry.
• Academic & Contract Research: Essential reagent for exploratory research in university and CRO laboratories.

Basic Information

Product Name	2H-1-Benzopyran-5-Carbonyl Chloride, 8-Fluoro- (9Ci)
CAS No.	214823-05-9
Molecular Formula	C10H6ClFO2
Molecular Weight	212.61 g/mol
Synonyms	8-Fluoro-2H-1-benzopyran-5-carbonyl chloride; 8-Fluorochromone-5-carbonyl chloride; 5-(Chlorocarbonyl)-8-fluoro-2H-chromen-2-one; 8-Fluoro-2-oxo-2H-chromene-5-carbonyl chloride; 214823-05-9; 8-Fluorochroman-5-carbonyl chloride (related structure); Fluorinated benzopyranoyl chloride
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-5-Carbonyl Chloride, 8-Fluoro- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.