Description

2,3-Difluoro-4-(trifluoromethyl)benzyl bromide is a high-value, multi-fluorinated benzyl bromide derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and bromine substituents, makes it an indispensable reagent for introducing functionalized aromatic motifs into target molecules. This compound is primarily sought after by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluoro and trifluoromethyl groups contribute to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies, leveraging its aromatic and halogenated structure.
• Organic Electronics: Employed in the creation of novel organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Cross-Coupling Reactions: Acts as an electrophilic partner in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Material Science Research: Utilized as a monomer or functionalization agent in the development of specialty polymers and advanced materials with specific surface properties.

Basic Information

Item	Details
Product Name	2,3-Difluoro-4-(trifluoromethyl)benzyl bromide
CAS No.	213203-85-1
Molecular Formula	C8H4BrF5
Molecular Weight	275.02 g/mol
Synonyms	α-Bromo-2,3-difluoro-4-(trifluoromethyl)toluene; (2,3-Difluoro-4-(trifluoromethyl)phenyl)methyl bromide; 2,3-Difluoro-α-bromo-4-(trifluoromethyl)toluene; 1-(Bromomethyl)-2,3-difluoro-4-(trifluoromethyl)benzene; Benzyl bromide, 2,3-difluoro-4-(trifluoromethyl)-; 2,3-Difluoro-4-trifluoromethylbenzyl Bromide
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-(trifluoromethyl)benzyl bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.