Description

5-Bromo-3',5'-Bis-o-Benzoyl-2'-Deoxy-2'-Fluoro-β-D-Arabinouridine is a high-purity, fluorinated nucleoside analog building block, critical for advanced pharmaceutical research and development. This compound is engineered to provide researchers with a reliable and structurally precise intermediate for the synthesis of novel therapeutic agents, particularly in the antiviral and anticancer fields. It is an essential raw material for specialized contract research organizations (CROs), pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in cutting-edge nucleoside chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Antiviral Drug Research: Used in the development of potential therapeutics targeting viruses such as hepatitis B (HBV) and other viral infections.
• Anticancer Agent Development: Serves as a precursor for creating nucleoside analogs designed to inhibit cancer cell proliferation.
• Pro-drug Synthesis: Utilized in the design and synthesis of pro-drug forms to enhance bioavailability and therapeutic efficacy.
• Biochemical Research: Employed in studies investigating enzyme mechanisms, DNA/RNA interactions, and cellular metabolism.
• Labeled Compound Synthesis: Acts as a starting material for the preparation of isotopically labeled compounds for pharmacokinetic and metabolic studies.

Basic Information

Product Name	5-Bromo-3',5'-Bis-o-Benzoyl-2'-Deoxy-2'-Fluoro-β-D-Arabinouridine
CAS No.	213136-12-0
Molecular Formula	C25H20BrFN2O7
Molecular Weight	559.34 g/mol
Synonyms	2'-Deoxy-2'-fluoro-5-bromo-3',5'-di-O-benzoyl-β-D-arabinouridine; 5-Bromo-2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-β-D-arabinouridine; 2'-Fluoro-5-bromo-3',5'-di-O-benzoyl-2'-deoxy-β-D-arabinouridine; 5-Br-FMAU 3',5'-dibenzoate; 5-Bromo-2'-fluoro-3',5'-di-O-benzoyl-arabinouridine; β-D-Arabinouridine, 5-bromo-2'-deoxy-2'-fluoro-3',5'-bis-O-(phenylcarbonate)
EINECS	Contact for details

Quality Control

Our 5-Bromo-3',5'-Bis-o-Benzoyl-2'-Deoxy-2'-Fluoro-β-D-Arabinouridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality management system is designed to meet the stringent requirements of pharmaceutical R&D and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.