Description

2',5'-Dideoxy-2'-Fluoro-5'-Iodouridine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and a versatile intermediate for the synthesis of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of nucleoside-based therapeutics, diagnostic probes, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA metabolism and viral replication.
• Probe Development: Serves as a building block for creating labeled nucleosides for diagnostic and imaging applications.
• Antiviral Agent Development: Investigated for its potential activity against a range of DNA and RNA viruses due to its modified sugar moiety.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2',5'-Dideoxy-2'-Fluoro-5'-Iodouridine
CAS No.	211694-25-6
Molecular Formula	C9H10FIN2O5
Molecular Weight	372.09 g/mol
Synonyms	2'-Deoxy-2'-fluoro-5'-iodouridine; 5'-Iodo-2',5'-dideoxy-2'-fluorouridine; 1-[(2R,3R,5S)-3-Fluoro-5-iodo-2-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione; 2'-F-5'-I-dU; 2'-Fluoro-5'-iodo-2',5'-dideoxyuridine; 5'-Iodo-2'-fluoro-2',5'-dideoxyuridine; FDUR-I; 2'-F-5'-I-Urd
EINECS	Contact for details

Quality Control

Our 2',5'-Dideoxy-2'-Fluoro-5'-Iodouridine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our global clientele in pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.