Description

p-Nitrophenyl 2-Azido-2-Deoxy-A-D-Galactopyranoside is a specialized glycoside derivative designed for advanced biochemical research and synthesis. This compound serves as a critical synthetic intermediate and biochemical probe, particularly valuable for studying carbohydrate-active enzymes and developing novel glycoconjugates. It is primarily utilized by research institutions and pharmaceutical companies engaged in enzymology, glycobiology, and the development of diagnostic tools or targeted therapeutics.

Application

• Enzyme Substrate & Inhibitor Studies: Acts as a chromogenic or photoaffinity substrate for glycosidases, transferases, and other carbohydrate-processing enzymes to investigate mechanism and kinetics.
• Glycoconjugate Synthesis: Serves as a key building block for the chemical and chemoenzymatic synthesis of complex oligosaccharides, glycopeptides, and glycolipids.
• Diagnostic Reagent Development: Used in the formulation of assay kits for the detection and quantification of specific enzyme activities in clinical or research samples.
• Chemical Biology Probes: The azido group enables bioorthogonal click chemistry (e.g., CuAAC, SPAAC) for labeling, imaging, and profiling carbohydrate-binding proteins in living systems.
• Pharmaceutical Intermediate: Employed in the research and development stages of novel therapeutic agents targeting carbohydrate-mediated biological processes.
• Academic & Industrial Research: A fundamental tool for basic research in glycoscience, supporting discoveries in cell biology, immunology, and microbiology.

Basic Information

Product Name	p-Nitrophenyl 2-Azido-2-Deoxy-A-D-Galactopyranoside
CAS No.	210418-04-5
Molecular Formula	C12H14N4O7
Molecular Weight	326.26 g/mol
Synonyms	4-Nitrophenyl 2-azido-2-deoxy-α-D-galactopyranoside; 2-Azido-2-deoxy-α-D-galactopyranosyl 4-nitrobenzoate; α-D-Galactopyranoside, 2-azido-2-deoxy-, 4-nitrophenyl; pNP-2-Azido-2-deoxy-α-D-galactopyranoside; 4-Nitrophenyl 2-azido-2-deoxy-α-D-galactoside; 2-Azido-2-deoxy-α-D-galactose 4-nitrophenyl glycoside
EINECS	Contact for details

Quality Control

Our p-Nitrophenyl 2-Azido-2-Deoxy-A-D-Galactopyranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure high consistency and reliability for research applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions for long-term stability. This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.