Description

4-Pyridin-2-Yl-Piperazine-1-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters for its role as a key building block in the development of complex, biologically active molecules, enabling precise molecular modifications. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies to introduce the 2-pyridylpiperazine pharmacophore into target molecules.
• Chemical Research & Development: Serves as a versatile reagent for constructing complex heterocyclic compounds and amide/urea derivatives in academic and industrial R&D labs.
• Agrochemical Synthesis: Employed in the development of advanced crop protection agents and pesticides requiring specific piperazine-based structures.
• Ligand Synthesis for Catalysis: Used to prepare specialized ligands for metal-catalyzed reactions in asymmetric synthesis.

Basic Information

Item	Detail
Product Name	4-Pyridin-2-Yl-Piperazine-1-Carbonyl Chloride
CAS No.	210173-95-8
Molecular Formula	C10H12ClN3O
Molecular Weight	225.67 g/mol
Synonyms	1-(2-Pyridinyl)piperazine-1-carbonyl chloride; 1-Piperazinecarbonyl chloride, 4-(2-pyridinyl)-; 4-(Pyridin-2-yl)piperazine-1-carbonyl chloride; 2-Pyridylpiperazine-1-carbonyl chloride; 1-(Pyridin-2-yl)piperazine-4-carbonyl chloride; 4-(2-Pyridyl)-1-piperazinecarbonyl chloride; 210173-95-8; 4-(2-Pyridinyl)-1-piperazinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Pyridin-2-Yl-Piperazine-1-Carbonyl Chloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.