Description

m-Peg7-Azide is a heterobifunctional polyethylene glycol (PEG) linker featuring a methoxy group at one terminus and a reactive azide group at the other. This compound is a critical reagent in bioconjugation and click chemistry, enabling the efficient, site-specific coupling of biomolecules, polymers, and surfaces under mild, aqueous conditions. It is essential for researchers and manufacturers in pharmaceutical development, biotech, and advanced materials science who require reliable, high-purity linkers for creating stable, functionalized conjugates.

Application

• Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Used to link cytotoxic drugs, fluorophores, or other payloads to antibodies, proteins, or peptides via strain-promoted azide-alkyne cycloaddition (SPAAC) or copper-catalyzed click chemistry (CuAAC).
• PEGylation and Drug Delivery Systems: Serves as a hydrophilic spacer to modify therapeutic proteins, peptides, or nanoparticles, improving solubility, stability, and pharmacokinetic profiles while reducing immunogenicity.
• Surface Functionalization and Biomaterial Engineering: Facilitates the covalent attachment of bioactive molecules to hydrogels, sensor surfaces, diagnostic chips, and medical device coatings to introduce specific biological functions.
• Polymer Chemistry and Dendrimer Synthesis: Acts as a versatile building block for constructing complex, branched polymer architectures and functional nanomaterials through step-growth polymerization.
• Diagnostic Reagent and Probe Synthesis: Enables the creation of fluorescent, radioactive, or affinity-based probes for imaging, biosensing, and in vitro diagnostic (IVD) applications.
• Crosslinking Agent: Used to create stable crosslinks between alkyne-functionalized molecules in the development of hydrogels, polymer networks, and affinity matrices.

Basic Information

Product Name	m-Peg7-Azide
CAS No.	208987-04-6
Molecular Formula	C16H33N3O8
Molecular Weight	395.45 g/mol
Synonyms	mPEG7-Azide; Methoxy-PEG7-Azide; Azido-PEG7-OMe; α-Methoxy-ω-azido heptaethylene glycol; 2-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl azide; Heptaethylene glycol monomethyl ether azide; mPEG7-N3; 1-Azido-2,5,8,11,14,17,20-heptaoxadocosane
EINECS	Contact for details

Quality Control

Our m-Peg7-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure high purity and batch-to-batch consistency suitable for research and commercial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional group integrity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under inert atmosphere (e.g., nitrogen or argon) for long-term stability. The product is moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Functional Group Assay (Azide)	≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.