Description

3-(2-Fluorophenyl)-2-Propenoylhloride is a specialized fluorinated organic acid chloride building block. This compound is valued for its high reactivity, enabling efficient synthesis of amides, esters, and other derivatives in complex organic frameworks. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and advanced agrochemical sectors for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probes: Employed in the development of activity-based probes and fluorescent tags for studying enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	3-(2-Fluorophenyl)-2-Propenoylhloride
CAS No.	208922-47-8
Molecular Formula	C9H6ClFO
Molecular Weight	184.59 g/mol
Synonyms	2-Fluorocinnamoyl Chloride; (E)-3-(2-Fluorophenyl)acryloyl chloride; trans-3-(2-Fluorophenyl)-2-propenoyl chloride; 3-(2-Fluorophenyl)acryloyl chloride; (2-Fluorophenyl)propenoyl chloride; α,β-Unsaturated acid chloride (fluorinated); 2-Fluorocinammic acid chloride
EINECS	Contact for details

Quality Control

Our production of 3-(2-Fluorophenyl)-2-Propenoylhloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized by multiple analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.