Description

N1-Methyladenosine Hydroiodide is a chemically modified nucleoside derivative, specifically the hydroiodide salt of N1-methyladenosine. This compound is of significant value as a key biochemical reagent and a critical building block in nucleic acid research and medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in epigenetics, RNA modification studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a standard or substrate in studies of RNA methylation, particularly investigating the role and function of N1-methyladenosine (m1A) modifications.
• Enzymology Studies: Serves as a reagent for studying methyltransferase and demethylase enzyme activity and kinetics related to adenosine modification.
• Pharmaceutical Intermediates: Acts as a crucial synthetic precursor or intermediate in the development of nucleoside-based antiviral or anticancer drugs.
• Diagnostic Development: Utilized in the synthesis of probes and tools for detecting and quantifying specific RNA modifications in diagnostic assays.
• Academic Research: Employed in universities and labs for fundamental research into epigenetic regulation, gene expression, and RNA biology.
• Reference Standard: Functions as a high-purity analytical reference standard for method development and validation in HPLC, LC-MS, or NMR analysis of modified nucleosides.

Basic Information

Product Name	N1-Methyladenosine Hydroiodide
CAS No.	208845-22-1
Molecular Formula	C11H16IN5O4
Molecular Weight	409.18 g/mol
Synonyms	1-Methyladenosine Hydroiodide; N(1)-Methyladenosine Hydroiodide; m1A Hydroiodide; Adenosine, 1-methyl-, hydroiodide; 9-β-D-Ribofuranosyl-1-methyladenine Hydroiodide; 1-Methyladenosine, hydroiodide salt; N-Methyladenosine Hydroiodide; 1-Methyl-9-β-D-ribofuranosyladenine Hydroiodide
EINECS	Contact for details

Quality Control

Our N1-Methyladenosine Hydroiodide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.