Description

2,3,5,6-Tetrafluorophenyl Isothiocyanate is a specialized fluorinated aromatic building block characterized by its reactive isothiocyanate functional group. This compound is critical for the synthesis of advanced materials and bioactive molecules where the introduction of a perfluorinated phenyl moiety is required. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel thiourea derivatives and other functionalized intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating thiourea-based protease inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides with enhanced activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the surface functionalization of polymers and nanoparticles to impart specific chemical and physical properties.
• Fluorescent Probe and Dye Synthesis: Acts as a reactive handle for attaching fluorophores to biological molecules or materials for sensing and imaging applications.
• Cross-linking Agent: Utilized in polymer chemistry to introduce covalent cross-links, modifying material strength and thermal stability.

Basic Information

Product Name	2,3,5,6-Tetrafluorophenyl Isothiocyanate
CAS No.	207981-49-5
Molecular Formula	C7HF4NS
Molecular Weight	207.15 g/mol
Synonyms	2,3,5,6-Tetrafluorophenyl isothiocyanate; Perfluorophenyl Isothiocyanate; 2,3,5,6-Tetrafluorobenzenisothiocyanate; NSC 339063; 1-Isothiocyanato-2,3,5,6-tetrafluorobenzene; Tetrafluorophenyl mustard oil; PFP-ITC
EINECS	Contact for details

Quality Control

Every batch of 2,3,5,6-Tetrafluorophenyl Isothiocyanate is produced and tested under strict quality management protocols to ensure consistency and high purity for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.