Description

N6 -(Diisobutylaminomethylidene)-2'-Deoxyisoguanosine is a specialized nucleoside analog with a modified purine base structure, designed for advanced research and development applications. This compound is valued for its role as a key synthetic intermediate and building block in the creation of novel pharmaceutical agents and biochemical probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly in the development of antiviral and anticancer therapeutics.

Application

• Medicinal Chemistry Research: Serves as a crucial synthetic intermediate in the design and synthesis of novel nucleoside-based drug candidates.
• Antiviral Drug Development: Investigated for its potential incorporation into oligonucleotide analogs targeting viral replication mechanisms.
• Oncology Research: Used as a building block for developing prodrugs and targeted therapies that interfere with cancer cell DNA/RNA synthesis.
• Biochemical Probes: Acts as a modified nucleoside for studying enzyme mechanisms, such as those of kinases and polymerases.
• Process Chemistry: Employed in scaling up synthetic routes for advanced pharmaceutical intermediates under GMP-like conditions.
• Academic Research: Utilized in universities and institutes for fundamental studies in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	N6 -(Diisobutylaminomethylidene)-2'-Deoxyisoguanosine
CAS No.	207981-31-5
Molecular Formula	C19H30N6O4
Molecular Weight	406.48 g/mol
Synonyms	2'-Deoxy-N6-(diisobutylaminomethylene)isoguanosine; N6-(Diisobutylaminomethylene)-2'-deoxyisoguanosine; 2'-Deoxyisoguanosine, N6-(diisobutylaminomethylene)-; 9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-(diisobutylaminomethylideneamino)purin-2-one; Isoguanosine derivative, N6-protected
EINECS	Contact for details

Quality Control

Our N6 -(Diisobutylaminomethylidene)-2'-Deoxyisoguanosine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemical synthesis, and specifications can be aligned with specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.