Description

2,2,2-Trifluoro-1-(3,4,5-Trimethoxyphenyl)Ethanol is a high-value trifluoromethylated synthetic intermediate with a distinct aromatic methoxy substitution pattern. This compound is critical for its role as a key building block in modern pharmaceutical and agrochemical research, enabling the introduction of both trifluoroethanol and trimethoxyphenyl pharmacophores. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel bioactive molecules, including potential CNS agents and anticancer compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a chiral building block for creating specialized ligands used in asymmetric catalysis.
• Material Science Precursor: Employed in the research of fluorinated polymers and advanced organic materials with unique electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and cellular processes.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) serving the global pharmaceutical pipeline.

Basic Information

Product Name	2,2,2-Trifluoro-1-(3,4,5-Trimethoxyphenyl)Ethanol
CAS No.	207502-47-4
Molecular Formula	C11H13F3O4
Molecular Weight	266.22 g/mol
Synonyms	1-(3,4,5-Trimethoxyphenyl)-2,2,2-trifluoroethanol; α-(Trifluoromethyl)-3,4,5-trimethoxybenzenemethanol; 2,2,2-Trifluoro-1-(3,4,5-trimethoxyphenyl)ethan-1-ol; 3,4,5-Trimethoxy-α-(trifluoromethyl)benzyl Alcohol; Benzenemethanol, α-(trifluoromethyl)-3,4,5-trimethoxy-; (3,4,5-Trimethoxyphenyl)(trifluoromethyl)methanol
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(3,4,5-Trimethoxyphenyl)Ethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.