Description

5'-GTP Trisodium Salt Hydrate is a high-purity nucleotide essential for biochemical research and pharmaceutical development. This compound serves as a critical substrate and energy donor in enzymatic reactions, particularly those involving RNA synthesis, protein translation, and signal transduction pathways. It is indispensable for researchers and manufacturers in molecular biology, enzymology, and diagnostic kit production, where precise and reliable nucleotide quality is paramount for experimental reproducibility and product efficacy.

Application

• Biochemical Research: Essential substrate for studies on GTP-binding proteins (G-proteins), polymerases, and kinases.
• Diagnostic Reagent Manufacturing: Key component in enzymatic assay kits for clinical diagnostics and life science research.
• Pharmaceutical Development: Used in cell-based assays for drug discovery targeting nucleotide-dependent pathways.
• Enzymology Studies: Serves as a phosphate donor or energy source in enzymatic reaction characterization.
• Molecular Biology: Utilized in in vitro transcription and translation systems.
• Cell Signaling Research: Critical for investigating cellular processes regulated by GTP, such as cytoskeleton dynamics and vesicle trafficking.

Basic Information

Product Name	5'-GTP Trisodium Salt Hydrate
CAS No.	207300-85-4
Molecular Formula	C10H14N5Na3O14P3 · xH2O
Molecular Weight	Approx. 605.1 (Anhydrous basis)
Synonyms	Guanosine-5'-triphosphate trisodium salt hydrate; GTP Na3 salt; 5'-Guanosine triphosphate trisodium; Sodium GTP; GTP trisodium; Trisodium guanosine 5'-triphosphate hydrate; Guanosine triphosphate trisodium salt
EINECS	Contact for details

Quality Control

Our 5'-GTP Trisodium Salt Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and LAL testing for endotoxins where applicable. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research-grade standards. Customized purity grades, including >95% and >98%, are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 10%
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (if specified)
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.