Description

2'-Deoxyadenosine-5'-Monophosphoric Acid is a vital nucleotide monophosphate, serving as a fundamental building block in nucleic acid synthesis and research. This high-purity biochemical is essential for applications demanding precise molecular structure and reliable performance, from enzymatic studies to the development of oligonucleotide-based therapeutics. It is a critical reagent for molecular biologists, pharmaceutical researchers, and diagnostic developers working in genomics, drug discovery, and biotechnology.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for the solid-phase synthesis of DNA strands and probes.
• Enzymatic Research: Used as a substrate or product in studies of kinases, polymerases, and other nucleotide-metabolizing enzymes.
• Pharmaceutical Development: Serves as an intermediate in the production of nucleotide analog antiviral and anticancer drugs.
• Diagnostic Assays: Incorporated into primers, probes, and standards for PCR, qPCR, and other molecular diagnostic techniques.
• Biochemical Standards: Employed as a high-purity reference standard for analytical method development and quality control.
• Cell Culture & Metabolism Studies: Used to investigate nucleotide salvage pathways and cellular energy metabolism.

Basic Information

Product Name	2'-Deoxyadenosine-5'-Monophosphoric Acid
CAS No.	207127-57-9
Molecular Formula	C10H14N5O6P
Molecular Weight	331.22 g/mol
Synonyms	2'-Deoxyadenosine 5'-monophosphate; dAMP; Deoxyadenylic acid; 5'-dAMP; 2'-Deoxy-5'-adenylic acid; Adenine deoxyribonucleotide; 9-(2-Deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)adenine
EINECS	Contact for details

Quality Control

Our 2'-Deoxyadenosine-5'-Monophosphoric Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically verified by HPLC, NMR, and MS. We adhere to relevant industry guidelines to support your compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.