Description

2'-Deoxyguanosine Hydrate, 99% is a high-purity nucleoside derivative essential for life science research and pharmaceutical development. This compound serves as a critical building block for oligonucleotide synthesis and is fundamental in studying DNA replication, repair mechanisms, and cellular metabolism. It is primarily utilized by researchers and manufacturers in the biotechnology, pharmaceutical, and diagnostic industries.

Application

• Oligonucleotide Synthesis: A vital phosphoramidite precursor for the solid-phase synthesis of DNA and RNA strands for research, diagnostics, and therapeutics.
• Biochemical Research: Used as a substrate in enzymatic studies, including investigations into kinase and polymerase activities.
• Pharmaceutical Intermediates: Serves as a key starting material in the development of antiviral and anticancer nucleoside analog drugs.
• Cell Culture & Media Supplement: Employed in specialized cell culture media to support the growth of certain fastidious cell lines.
• Diagnostic Reagent Manufacturing: Incorporated into probes and primers for PCR, sequencing, and other molecular biology techniques.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, and NMR.

Basic Information

Product Name	2'-Deoxyguanosine Hydrate, 99%
CAS No.	207121-55-9
Molecular Formula	C10H13N5O4 · xH2O
Molecular Weight	267.24 (Anhydrous basis)
Synonyms	2'-Deoxyguanosine Monohydrate; Deoxyguanosine Hydrate; 9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,9-dihydro-6H-purin-6-one Hydrate; dG Hydrate; Guanine Deoxyriboside Hydrate; 2'-dG Hydrate; 2'-Deoxy-D-guanosine Hydrate
EINECS	Contact for details

Quality Control

Our 2'-Deoxyguanosine Hydrate, 99% is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content to ensure it meets the stringent requirements of research and development. Certificates of Analysis (COA) with lot-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric humidity. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 99.0%
Water Content (KF)	≤ 8.0%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.