Description

2,4,6-Trifluorophenyl Isothiocyanate is a specialized fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive isothiocyanate group, which readily undergoes addition and cyclization reactions, enabling the efficient construction of complex heterocyclic scaffolds. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing fluorinated thiazole, benzothiazole, and thiourea derivatives with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that benefit from the metabolic stability imparted by fluorine atoms.
• Material Science Research: Serves as a monomer or coupling agent in the creation of specialized polymers and liquid crystals with unique electronic properties.
• Chemical Biology & Proteomics: Acts as an electrophilic probe for labeling cysteine residues in proteins or as a scaffold for activity-based protein profiling (ABPP) reagents.
• Ligand Synthesis: Building block for creating fluorinated ligands used in catalysis and metal-organic frameworks (MOFs).
• Dye & Pigment Intermediate: Employed in the synthesis of fluorinated chromophores for advanced imaging and sensing applications.

Basic Information

Item	Details
Product Name	2,4,6-Trifluorophenyl Isothiocyanate
CAS No.	206761-91-3
Molecular Formula	C7H2F3NS
Molecular Weight	197.16 g/mol
Synonyms	2,4,6-Trifluorophenyl isothiocyanate; 1-Isothiocyanato-2,4,6-trifluorobenzene; 2,4,6-Trifluorobenzene isothiocyanate; 2,4,6-Trifluorophenyl mustard oil; NSC 339063; Isothiocyanic acid, 2,4,6-trifluorophenyl ester
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluorophenyl Isothiocyanate is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its highly volatile nature, the container must be kept tightly sealed when not in use and stored at temperatures between 2°C and 8°C (refrigerated) for long-term stability. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.