Description

2,5-Difluorophenyl Isothiocyanate is a versatile and highly reactive aromatic isothiocyanate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the difluorophenyl moiety and the reactive isothiocyanate group, enabling the construction of complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients, intermediates for drug discovery, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for kinase inhibitors, receptor antagonists, and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, where the difluorophenyl group can enhance metabolic stability and bioavailability.
• Ligand and Probe Development: Employed in medicinal chemistry for creating chemical probes, fluorescent tags, or affinity ligands to study biological targets and pathways.
• Material Science Research: Acts as a monomer or cross-linking agent in the synthesis of specialized polymers, resins, or coatings with unique chemical resistance or surface properties.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects, supporting R&D efforts in fine chemical and specialty chemical production.

Basic Information

Product Name	2,5-Difluorophenyl Isothiocyanate
CAS No.	206559-57-1
Molecular Formula	C7H3F2NS
Molecular Weight	171.17 g/mol
Synonyms	1,4-Difluoro-2-isothiocyanatobenzene; 2,5-Difluorophenyl Mustard Oil; 2,5-Difluorobenzene Isothiocyanate; Isothiocyanic Acid 2,5-Difluorophenyl Ester; 2,5-Difluorophenylthiocarbonyl Imide; (2,5-Difluorophenyl) Isothiocyanate; 2,5-Difluorophenyl Isosulfocyanate
EINECS	Contact for details

Quality Control

Our 2,5-Difluorophenyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.