Description

Rac trans-Lafutidine CAS NO 206449-94-7 is a stereoisomeric form of Lafutidine, a histamine H2-receptor antagonist. This compound is of significant value as a key intermediate and reference standard in pharmaceutical research and development. It is primarily utilized by R&D chemists and quality control laboratories in the pharmaceutical industry for analytical method development, impurity profiling, and process chemistry.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments and the qualification of methods in drug development and quality control.
• Process Research & Development: Serves as a critical intermediate or starting material in the synthesis and optimization of active pharmaceutical ingredients (APIs).
• Impurity Identification and Profiling: Employed as a known impurity standard to monitor and control the quality of Lafutidine or related pharmaceutical batches.
• Metabolite Studies: Used in preclinical and clinical research to investigate the metabolic pathways of related therapeutic agents.
• Academic and Contract Research: Supports chemical and pharmacological research in academic institutions and CROs (Contract Research Organizations).

Basic Information

Product Name	Rac trans-Lafutidine
CAS No.	206449-94-7
Molecular Formula	C22H29N3O4S
Molecular Weight	431.55 g/mol
Synonyms	rac-trans-Lafutidine; (±)-trans-Lafutidine; 2-[(2-Furanylmethyl)sulfinyl]-N-[[4-[[4-(piperidin-1-ylmethyl)-2-pyridinyl]oxy]-(Z)-2-butenyl]acetamide; UNII-0J6I2J2V8F; FRG-8813 (trans racemate); Lafutidine Racemic Trans Isomer
EINECS	Contact for details

Quality Control

Our Rac trans-Lafutidine is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR, to ensure it meets high-purity standards suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.