Description

S,S- Albaconazole is a potent and stereochemically defined triazole antifungal agent. Its primary value lies in its targeted mechanism of action, which inhibits fungal ergosterol biosynthesis, offering high efficacy against a broad spectrum of pathogens. This compound is essential for research and development within the pharmaceutical industry, particularly for advancing novel antifungal therapeutics and studying sterol biosynthesis pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of advanced antifungal drug candidates.
• Biochemical Research: Used as a reference standard and active compound in studies targeting fungal CYP51 (lanosterol 14α-demethylase) enzyme inhibition.
• Antifungal Agent Development: A key starting material for the research and development of new triazole-based therapeutic agents for human and veterinary medicine.
• Microbiology Studies: Employed in in-vitro assays to determine antifungal activity spectra and minimum inhibitory concentrations (MICs) against various fungal strains.
• Mechanism of Action Research: Utilized to investigate the structure-activity relationship (SAR) and resistance mechanisms in pathogenic fungi.

Basic Information

Product Name	S,S- Albaconazole
CAS No.	206350-09-6
Molecular Formula	C₂₃H₂₀F₂N₄O
Molecular Weight	406.43 g/mol
Synonyms	Albaconazole (S,S-isomer); UNII-5W8V8355YT; (2S,3S)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-(4-fluorophenyl)butan-2-ol; (2S,3S)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-(4-fluorophenyl)-2-butanol; UR-9825 (S,S-isomer)
EINECS	Contact for details

Quality Control

Our S,S- Albaconazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets high-purity standards suitable for research and development. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% (S,S-isomer)
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.