Description

1-[2,5-Anhydro-4-C-(Hydroxymethyl)-α-L-Lyxofuranosyl]-5-Methyl-2,4(1H,3H)-Pyrimidinedione is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel antiviral and anticancer agents, enabling the exploration of new therapeutic mechanisms. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Antiviral Research: Used in the development of experimental therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a precursor for compounds being investigated for their antiproliferative and cytotoxic activities.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate nucleic acid metabolism and related pathways.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	1-[2,5-Anhydro-4-C-(Hydroxymethyl)-α-L-Lyxofuranosyl]-5-Methyl-2,4(1H,3H)-Pyrimidinedione
CAS No.	206055-67-6
Molecular Formula	C11H14N2O6
Molecular Weight	270.24 g/mol
Synonyms	5-Methyl-2'-deoxyuridine analog; 1-(2,5-Anhydro-4-C-hydroxymethyl-α-L-lyxofuranosyl)-5-methyluracil; 5-Methyldeoxyuridine derivative; Anhydro nucleoside; Lyxofuranosyl pyrimidinedione; Nucleoside intermediate; Research chemical 206055-67-6
EINECS	Contact for details

Quality Control

Our 1-[2,5-Anhydro-4-C-(Hydroxymethyl)-α-L-Lyxofuranosyl]-5-Methyl-2,4(1H,3H)-Pyrimidinedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.