Description

Benzoyl Chloride, 2-(1-Propynyl)- (9Ci) CAS NO 205250-13-1 is a specialized organic building block featuring a benzoyl chloride core functionalized with a propargyl group at the ortho position. This unique structure makes it a valuable intermediate for synthesizing complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and agrochemical industries for constructing novel compounds with targeted biological or material properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), especially those requiring an ortho-substituted benzoyl moiety.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its propargyl group enables unique modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers or functional units for polymers with specific optical or electronic properties.
• Chemical Biology Probes: Useful for creating tagged molecules or activity-based probes due to the reactivity of both the acid chloride and alkyne functional groups.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the biotechnology and specialty chemical sectors.

Basic Information

Product Name	Benzoyl Chloride, 2-(1-Propynyl)- (9Ci)
CAS No.	205250-13-1
Molecular Formula	C10H7ClO
Molecular Weight	178.62 g/mol
Synonyms	2-(Prop-1-yn-1-yl)benzoyl chloride; 2-(1-Propynyl)benzoyl chloride; o-(1-Propynyl)benzoyl chloride; Benzoyl chloride, 2-(1-propynyl)-; 2-Propynylbenzoyl chloride; 1-(2-Chlorocarbonylphenyl)propyne; 205250-13-1; (2-Prop-1-ynylphenyl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of Benzoyl Chloride, 2-(1-Propynyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent hydrolysis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.