Description

6-Chloro-9-(2-C-Methyl-β-D-Ribofuranosyl)-9H-Purine is a high-purity nucleoside analog, a critical building block in advanced pharmaceutical synthesis. This compound matters for its role as a key intermediate in the development of novel antiviral and anticancer therapeutics, where precise molecular structure is paramount for biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in nucleoside chemistry, medicinal chemistry, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of modified nucleoside-based antiviral and anticancer drugs.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Nucleoside Analog Synthesis: Used in the preparation of C-methylated ribonucleoside analogs for biological evaluation.
• Biochemical Research: Employed in studies investigating enzyme inhibition and metabolic pathways involving purine nucleotides.
• API Development: Integrated into the manufacturing process of complex Active Pharmaceutical Ingredients (APIs) requiring high stereochemical purity.

Basic Information

Product Name	6-Chloro-9-(2-C-Methyl-β-D-Ribofuranosyl)-9H-Purine
CAS No.	205171-05-7
Molecular Formula	C11H13ClN4O4
Molecular Weight	300.70 g/mol
Synonyms	2'-C-Methyl-6-chloropurine riboside; 6-Chloro-2'-C-methylpurine ribonucleoside; 6-Chloro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-methyloxolan-2-yl]purine; 6-Chloro-2'-methyladenosine analog; 2'-C-Methyl-6-chloropurine nucleoside; 6-Chloro-2'-C-methyl-β-D-ribofuranosylpurine; 205171-05-7
EINECS	Contact for details

Quality Control

Our 6-Chloro-9-(2-C-Methyl-β-D-Ribofuranosyl)-9H-Purine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.