Description

5-Methyl-1-Phenyl-1H-Pyrazole-4-Carbonyl Chloride is a versatile and highly reactive organic intermediate, primarily used as a key building block in advanced chemical synthesis. Its value lies in its ability to readily form amide or ester bonds, making it indispensable for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require a reliable and high-purity acylating agent.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing the pyrazole core, which is common in various therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyrazole moiety contributes to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of novel polymers and functional materials with specific thermal or chemical properties.
• Ligand and Catalyst Development: Employed in organic and organometallic chemistry to create novel ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and academic laboratories exploring new chemical entities and reaction pathways.

Basic Information

Product Name	5-Methyl-1-Phenyl-1H-Pyrazole-4-Carbonyl Chloride
CAS No.	205113-77-5
Molecular Formula	C11H9ClN2O
Molecular Weight	220.66 g/mol
Synonyms	5-Methyl-1-phenyl-1H-pyrazole-4-carbonyl chloride; 1-Phenyl-5-methyl-1H-pyrazole-4-carbonyl chloride; 5-Methyl-1-phenylpyrazole-4-carbonyl chloride; 4-Pyrazolecarbonyl chloride, 5-methyl-1-phenyl-; 205113-77-5; 5-Methyl-1-phenyl-1H-pyrazole-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 5-Methyl-1-Phenyl-1H-Pyrazole-4-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in common organic solvents (DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.