Description

5-Quinolinecarbonyl Chloride, 8-Methyl- (9Ci) is a high-purity, reactive chemical intermediate belonging to the quinoline family. This compound matters for its role as a versatile acyl chloride building block, enabling the synthesis of complex amides and esters under controlled conditions. It is primarily needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the quinoline scaffold can impart specific biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of advanced polymers with specialized optical or electronic properties.
• Ligand Synthesis: Employed to prepare complex chelating agents and catalysts for use in asymmetric synthesis and metal-catalyzed reactions.
• Fluorescent Probe Development: The quinoline core is utilized to construct sensitive molecular probes for bioimaging and diagnostic applications.
• Academic & Contract Research: A valuable reagent for exploratory chemistry in university laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	5-Quinolinecarbonyl Chloride, 8-Methyl- (9Ci)
CAS No.	204783-04-0
Molecular Formula	C11H8ClNO
Molecular Weight	205.64 g/mol
Synonyms	8-Methylquinoline-5-carbonyl chloride; 8-Methyl-5-quinolinecarbonyl chloride; 5-Carbamoyl-8-methylquinoline chloride; 8-Methyl-5-quinolinecarboxylic acid chloride; 204783-04-0; 8-Methylquinoline-5-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 5-Quinolinecarbonyl Chloride, 8-Methyl- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.