Description

2-Bromo-5-Fluorobenzyl Alcohol is a versatile fluorinated and brominated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional halogenated structure makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by pharmaceutical, agrochemical, and specialty chemical R&D departments for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine and bromine substituents enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystal compounds and electron-transport/hole-blocking materials in organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The benzyl alcohol and aryl bromide functionalities make it a suitable substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Protecting Group Chemistry: Can be used to introduce the benzyloxy group or be further modified, acting as a protecting group precursor in multi-step syntheses.
• Material Science Research: Employed in the synthesis of novel polymers, ligands for catalysis, and advanced organic frameworks.

Basic Information

Product Name	2-Bromo-5-Fluorobenzyl Alcohol
CAS No.	202865-66-5
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	(2-Bromo-5-fluorophenyl)methanol; 5-Fluoro-2-bromobenzyl alcohol; 2-Bromo-5-fluorobenzenemethanol; α-Hydroxymethyl-2-bromo-5-fluorobenzene; 1-Bromo-4-fluoro-2-(hydroxymethyl)benzene; 2-Bromo-5-fluoro-1-hydroxymethylbenzene; Benzenemethanol, 2-bromo-5-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluorobenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.