Description

(+)-Talarozole CAS NO 201410-66-4 is a high-purity, enantiomerically pure small molecule compound belonging to the class of retinoic acid metabolism-blocking agents (RAMBAs). This compound is of significant interest in pharmaceutical research and development due to its specific biological activity. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for advanced drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents.
• Retinoic Acid Pathway Research: Used as a reference standard and active compound in studies investigating retinoic acid metabolism and signaling pathways.
• Dermatological Research: Applied in preclinical research for conditions like psoriasis, acne, and other skin disorders influenced by retinoid levels.
• Oncology Research: Investigated for its potential role in cancer research, particularly in differentiation therapy.
• Biochemical Tool Compound: Employed in vitro and in vivo to study the effects of modulating endogenous retinoic acid concentrations.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.

Basic Information

Product Name	(+)-Talarozole
CAS No.	201410-66-4
Molecular Formula	C₂₁H₂₁N₃O₂
Molecular Weight	347.41 g/mol
Synonyms	(+)-Talarozole; R115866; Talarozole; R 115866; (R)-N-[4-[2-Ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl]-2-benzothiazolamine; (R)-N-(4-(2-Ethyl-1-(1H-1,2,4-triazol-1-yl)butyl)phenyl)benzo[d]thiazol-2-amine
EINECS	Contact for details

Quality Control

Our (+)-Talarozole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (HPLC), and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.