Description

2-Thiazolecarbonylchloride,4-(Chloromethyl)-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its dual reactive sites—the acid chloride and chloromethyl groups—which enable precise, sequential functionalization to create complex molecular architectures. Pharmaceutical, agrochemical, and material science R&D teams require this high-purity intermediate for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel thiazole-containing drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and plant growth regulators with thiazole cores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: Employed to introduce thiazole functionalities into polymers, potentially modifying thermal, optical, or electronic properties.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and molecular tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-Thiazolecarbonylchloride,4-(Chloromethyl)-(9Ci)
CAS No.	200418-16-2
Molecular Formula	C5H3Cl2NOS
Molecular Weight	196.05 g/mol
Synonyms	4-(Chloromethyl)thiazole-2-carbonyl chloride; 2-Thiazolecarbonyl chloride, 4-(chloromethyl)-; 4-(Chloromethyl)-1,3-thiazole-2-carbonyl chloride; 4-(Chloromethyl)-2-thiazolecarbonyl chloride; 4-Chloromethylthiazole-2-carbonyl chloride; 2-Carbonylchloride-4-chloromethylthiazole; 200418-16-2; 4-(Chloromethyl)thiazole-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Thiazolecarbonylchloride,4-(Chloromethyl)-(9Ci) is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting R&D and process development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.