Description

2'-Deoxy-3',5'-Di-o-(4-Methylbenzoyl)-5-Ethyluridine is a key protected nucleoside derivative, specifically designed as a critical synthetic intermediate in advanced organic and medicinal chemistry. Its primary value lies in enabling the precise and efficient synthesis of modified oligonucleotides and nucleoside analogs, where protecting groups are essential for controlling regioselectivity. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly in the creation of antiviral and anticancer agents, as well as in the production of specialty fine chemicals and diagnostic probes.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Oligonucleotide Synthesis: Used in the preparation of modified DNA/RNA strands for research, diagnostics, and therapeutic applications.
• Prodrug Development: Serves as a precursor in the design of prodrugs to enhance the bioavailability and targeting of active nucleoside compounds.
• Biochemical Research: Employed in studies investigating nucleic acid chemistry, enzyme mechanisms, and cellular processes.
• Fine Chemical Synthesis: Acts as a specialized intermediate in custom synthesis and contract manufacturing for high-value chemical products.

Basic Information

Product Name	2'-Deoxy-3',5'-Di-o-(4-Methylbenzoyl)-5-Ethyluridine
CAS No.	29900-44-5
Molecular Formula	C27H28N2O7
Molecular Weight	492.52 g/mol
Synonyms	5-Ethyl-2'-deoxy-3',5'-di-O-(p-toluoyl)uridine; 5-Ethyl-2'-deoxyuridine 3',5'-di-p-toluate; 3',5'-Di-O-(4-methylbenzoyl)-5-ethyl-2'-deoxyuridine; 2'-Deoxy-5-ethyluridine 3',5'-dip-toluate; Protected 5-Ethyl-2'-deoxyuridine; p-Toluoyl-protected nucleoside; 5-Ethyl-dU 3',5'-di-p-toluoyl ester
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-3',5'-Di-o-(4-Methylbenzoyl)-5-Ethyluridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.