Description

5-Aminocarbonylmethyl-2-Thiouridine is a modified nucleoside derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and a key intermediate in the synthesis of novel oligonucleotides and therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, molecular biology, and the development of nucleotide-based therapeutics. Its unique structure offers valuable properties for probing biological mechanisms and creating targeted molecular tools.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used as a modified building block for creating labeled or functionalized DNA/RNA probes for diagnostic and research applications.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate RNA metabolism and modification pathways.
• Antisense Technology: A potential component in the development of antisense oligonucleotides for therapeutic gene silencing.
• Chemical Biology Tool: Useful for studying tRNA structure and function, as well as other nucleoside-related biological processes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5-Aminocarbonylmethyl-2-Thiouridine
CAS No.	29900-40-1
Molecular Formula	C11H15N3O7S
Molecular Weight	333.32 g/mol
Synonyms	5-Carbamoylmethyl-2-thiouridine; 2-Thio-5-carbamoylmethyluridine; 5-(Aminocarbonylmethyl)-2-thiouridine; 2-Thiouridine, 5-(aminocarbonylmethyl)-; 5-(Carbamoylmethyl)-2-thiouridine; Uridine, 5-(aminocarbonylmethyl)-2-thio-; 2-Thio-5-(carbamoylmethyl)uridine
EINECS	Contact for details

Quality Control

Our 5-Aminocarbonylmethyl-2-Thiouridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.