Description

2',3'-Di-o-Acetyladenosine is a chemically modified nucleoside derivative where acetyl groups protect the 2' and 3' hydroxyl positions of the ribose sugar. This compound matters as a crucial protected intermediate in oligonucleotide synthesis and pharmaceutical research, enabling precise chemical manipulation of the adenosine scaffold. It is primarily needed by manufacturers and researchers in the pharmaceutical, biotechnology, and diagnostic sectors for developing nucleoside-based therapeutics, prodrugs, and advanced biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Serves as a protected monomer in solid-phase synthesis of RNA and modified DNA sequences.
• Biochemical Research: Used in enzymatic studies and as a precursor for labeled nucleosides in tracer applications.
• Prodrug Development: The acetyl groups can be utilized in prodrug strategies to enhance bioavailability of active nucleoside drugs.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories.

Basic Information

Product Name	2',3'-Di-o-Acetyladenosine
CAS No.	29886-19-9
Molecular Formula	C₁₄H₁₇N₅O₆
Molecular Weight	351.32 g/mol
Synonyms	2',3'-Di-O-acetyladenosine; Adenosine, 2',3'-diacetate; 2',3'-Diacetyladenosine; 2',3'-O-Diacetyladenosine; 9-β-D-Ribofuranosyladenine 2',3'-diacetate; N6-Amino-9-(2,3-di-O-acetyl-β-D-ribofuranosyl)purine; 2',3'-Diacetyl-adenosine
EINECS	Contact for details

Quality Control

Our 2',3'-Di-o-Acetyladenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.