Description

Acetic Acid (20S,25R)-26-Hydroxy-16,22-Dioxocholest-5-En-3β-Yl Ester is a high-purity, specialized steroid derivative used as a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role in the research and development of novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers serving the global life sciences industry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new drug candidates targeting hormone receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating steroid metabolism, enzyme inhibition, and cellular signaling pathways.
• Process Development: Utilized for scaling up and optimizing synthetic routes in pilot plant and commercial manufacturing settings.

Basic Information

Product Name	Acetic Acid (20S,25R)-26-Hydroxy-16,22-Dioxocholest-5-En-3β-Yl Ester
CAS No.	29853-25-6
Molecular Formula	C₂₉H₄₄O₆
Molecular Weight	500.66 g/mol
Synonyms	(20S,25R)-26-Hydroxy-16,22-dioxocholest-5-en-3β-yl acetate; 3β-Acetoxy-(20S,25R)-26-hydroxy-16,22-dioxocholest-5-ene; 26-Hydroxy-16,22-dioxocholest-5-en-3β-yl acetate; 16,22-Dioxo-26-hydroxycholest-5-en-3β-yl acetate; Steroid derivative 29853-25-6; Cholestane derivative acetate ester
EINECS	Contact for details

Quality Control

Our Acetic Acid (20S,25R)-26-Hydroxy-16,22-Dioxocholest-5-En-3β-Yl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.