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2-Acetamido-2-Deoxy-β-D-Glucopyranosyl Azide CAS NO 29847-23-2


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CAS No.:29847-23-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Acetamido-2-Deoxy-β-D-Glucopyranosyl Azide is a specialized carbohydrate derivative and a key azido-functionalized glycosyl building block. This compound matters for its role as a versatile intermediate in the synthesis of complex glycoconjugates and neoglycoproteins via click chemistry, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is essential for researchers and manufacturers in pharmaceutical development, chemical biology, and glycochemistry who require high-purity, reactive intermediates for constructing biologically active molecules.

Application

  • Glycoconjugate Synthesis: A critical precursor for the chemoselective construction of glycopeptides, glycolipids, and neoglycoproteins via click chemistry methodologies.
  • Pharmaceutical Intermediates: Used in the research and development of novel therapeutics, including vaccine candidates and targeted drug delivery systems.
  • Chemical Biology Probes: Enables the labeling and study of carbohydrate-protein interactions and cellular processes through bioorthogonal tagging.
  • Material Science: Serves as a monomer or cross-linker for creating functionalized polymers and biomaterials with specific carbohydrate motifs.
  • Diagnostic Reagent Development: Employed in the design of diagnostic assays and imaging agents that target carbohydrate-binding proteins.

Basic Information

Product Name 2-Acetamido-2-Deoxy-β-D-Glucopyranosyl Azide
CAS No. 29847-23-2
Molecular Formula C8H14N4O5
Molecular Weight 246.22 g/mol
Synonyms 2-Acetamido-2-deoxy-β-D-glucopyranosyl azide; β-D-Glucopyranosyl azide, 2-acetamido-2-deoxy-; N-Acetyl-β-D-glucosaminyl azide; 1-Azido-2-acetamido-2-deoxy-β-D-glucopyranose; GlcNAz; Azido-GlcNAc; 2-Acetamido-2-deoxy-1-azido-β-D-glucopyranose; 1-Azido-2-deoxy-2-(acetylamino)-β-D-glucopyranose
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Quality Control

Our 2-Acetamido-2-Deoxy-β-D-Glucopyranosyl Azide is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability, consistency, and compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) in a cool, dry, and well-ventilated place. This material is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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