Description

2-Pyridinecarboxylicacid Chloride is a versatile and highly reactive acyl chloride derivative of picolinic acid, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 2-pyridylcarbonyl moiety, a key structural feature in many pharmacologically active compounds and functional materials. This intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to create active ingredients, ligands, and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing nicotinic acid or picolinic acid derivatives.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that require the pyridinecarboxylate functional group.
• Ligand and Catalyst Preparation: Essential for synthesizing complex ligands used in coordination chemistry and homogeneous catalysis.
• Peptide Mimetics and Bio-conjugation: Employed in the acylation of amines to create amide bonds in peptide-like structures and for labeling biomolecules.
• Material Science Research: Serves as a monomer or modifying agent in the development of advanced polymers and functional organic materials.
• Chemical Research & Development: A fundamental reagent for academic and industrial R&D exploring new heterocyclic compounds and reaction methodologies.

Basic Information

Product Name	2-Pyridinecarboxylicacid Chloride
CAS No.	29745-44-6
Molecular Formula	C6H4ClNO
Molecular Weight	141.56 g/mol
Synonyms	Picolinoyl Chloride; 2-Picolinoyl Chloride; Pyridine-2-carbonyl Chloride; 2-Pyridinecarbonyl Chloride; α-Picolinoyl Chloride; 2-Carboxypyridine Chloride; Picolinic Acid Chloride; Picolinic Chloride
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxylicacid Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.