Description

5-Carbamoylmethyluridine is a modified nucleoside building block of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical intermediate in the synthesis of oligonucleotides and modified RNA molecules, enabling the study of genetic regulation and therapeutic mechanisms. It is primarily utilized by research institutions, diagnostic developers, and pharmaceutical companies engaged in nucleic acid chemistry, antisense technology, and the creation of novel therapeutic agents.

Application

• Oligonucleotide Synthesis: A key monomer for the solid-phase synthesis of modified RNA strands for research and therapeutic applications.
• Antisense & RNA Therapeutics: Used in the development of antisense oligonucleotides (ASOs) and siRNA molecules that target specific genes.
• Biochemical Research: Employed as a substrate or intermediate in enzymatic studies and metabolic pathway investigations involving nucleotide analogs.
• Diagnostic Probe Development: Incorporated into labeled probes for detecting specific RNA sequences in diagnostic assays.
• Pharmaceutical Intermediates: Serves as a high-purity building block in the synthesis of more complex nucleoside-based active pharmaceutical ingredients (APIs).
• Academic Research: Fundamental studies in organic chemistry, medicinal chemistry, and molecular biology to explore structure-activity relationships.

Basic Information

Item	Details
Product Name	5-Carbamoylmethyluridine
CAS No.	29569-30-0
Molecular Formula	C11H15N3O7
Molecular Weight	301.25 g/mol
Synonyms	5-Carbamoylmethyluridine; 5-[(Aminocarbonyl)methyl]uridine; Uridine, 5-(carbamoylmethyl)-; 5-Carbamoylmethyl-uridine; 5-(Carbamoylmethyl)uridine; 5-N-Carbamoylmethyluridine; 5-CM-uridine; 5-Carbamoylmethyl-Urd
EINECS	Contact for details

Quality Control

Our 5-Carbamoylmethyluridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.