Description

Bufadienolide is a specialized class of cardioactive steroid compounds derived from natural sources, known for their potent biological activity. Its unique structural framework makes it a critical intermediate and reference standard in pharmaceutical research and development. This high-purity compound is essential for researchers and manufacturers in the life sciences sector, particularly those focused on cardiovascular drug discovery, toxicology studies, and the synthesis of novel therapeutic agents. Bufadienolide CAS NO 29565-35-3 represents a key building block for advancing scientific and medical innovation.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for quality control and analytical method development in drug manufacturing.
• Cardiovascular Research: Used as a lead compound or pharmacological tool in studying Na+/K+-ATPase inhibition and related cardiac effects.
• Natural Product Synthesis: Acts as a crucial intermediate in the semi-synthesis or total synthesis of complex steroid-based molecules.
• Biochemical Assays: Employed in high-throughput screening and in vitro assays to investigate specific biological pathways and mechanisms of action.
• Toxicology Studies: Utilized as a model compound to understand the toxicological profile of bufadienolide-class substances.
• Academic Research: Supports fundamental research in medicinal chemistry, pharmacology, and structural biology at universities and institutes.

Basic Information

Product Name	Bufadienolide
CAS No.	29565-35-3
Molecular Formula	C24H34O5
Molecular Weight	402.53 g/mol
Synonyms	Bufadienolide; Bufanolide; 14β,15β-Epoxy-3β,5β,14-trihydroxy-19-oxobufa-20,22-dienolide; 3β,5β,14-Trihydroxy-19-oxo-bufa-20,22-dienolide; 19-Oxobufalin; NSC 83265; Bufadienolide A; Scillarenin
EINECS	Contact for details

Quality Control

Our Bufadienolide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods (NMR, IR, MS) for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.